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academic.oup.com, doi:10.1086/588670

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However, evidence shows that hepatic glutamine synthetase contributes to both enteral and systemic ammonia detoxification (Hussinger, 1983

Another plausible mechanism by which CLA modulates body composition and weight loss is related to PPARs, especially PPAR, as CLA can reduce the expression of lipogenesis-related genes and decrease body fat by inhibiting PPAR [92]