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This suggests that the level of expression and activity of these two integrins could essentially create on/off switches in the TM/SC pathway that could regulate the homeostatic properties of the tissue

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Cell 167 , 9851000.e1021 (2016)

Importantly, despite recent research indicating distinct findings regarding the 40 Hz effect, particularly concerning amyloid load in AD 21,22 , multiple studies in both mouse models and humans have consistently affirmed the beneficial effects of GENUS on disease pathology 18,19,23,24,25,26,27,28,29,30