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Ubiquitin-specific protease 4 is an endogenous negative regulator of metabolic dysfunctions in nonalcoholic fatty liver disease in mice

3.3.2 Enhancing cellular therapies through microbiotaBA axis modulation Although direct clinical evidence is limited, compelling mechanistic data suggest that modulating the gut microbiotaBA axis may augment cellular immunotherapies such as Chimeric Antigen Receptor T (CAR-T) cell therapy

doi: 10.21273/HORTSCI.46.12.1650 161 TolisanoC.Del BuonoD

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By combining rigorous preclinical assessment, careful clinical trial design, and adherence to regulatory standards, natural antibacterial compounds can be effectively developed into ocular TB therapies