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Do not use if you or your family have a history of a type of thyroid cancer called MTC or MEN 2

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It also controls swelling to keep balance in the immune system

Avoid ice directly on skin, which can cause additional damage

Ideally incorporate rigorous baseline and follow-up assessments: DEXA, body composition, visceral fat, renal function, endocrine panels, inflammatory biomarkers (IL-6, TNF-, SASP markers if available)