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Mol Cell 39(2):171183

Resveratrol attenuates trimethylamine-N-oxide (TMAO)-induced atherosclerosis by regulating TMAO synthesis and bile acid metabolism via remodeling of the gut microbiota

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After treating MCF-7/ADR cells (an adriamycin-resistant cell line) with low-dose Paris saponin VII and adriamycin at different concentrations (0100 M), the combination enhanced the intracellular adriamycin fluorescence signal, significantly reduced the IC value of adriamycin in drug-resistant cells, and promoted apoptosis