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Description

All mechanistic descriptions above are derived from controlled laboratory investigations

Bournazos, S

10.3748/wjg.v22.i41.9127 15 DrmicD.KolencD.IlicS.BaukL.SeverM.SeverZ.et al (2017)

Jumping straight to a high dose would increase the likelihood of side effects such as nausea and digestive discomfort

214 Comparable outcomes have been observed in murine macrophages exposed to copper oxide nanoparticles, which induce oxidative stress and activate the NLRP3 inflammasome, leading to the expression of pro-IL-1 through the myeloid differentiation factor 88 (MyD88)-dependent TLR4 signaling pathway, subsequently activating NF-B in macrophages