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Since isoflavones have a structure and size similar to that of estrogen (in particular to estradiol, 17--estradiol, E2), they are often referred to as phytoestrogens and have been shown to exert multiple estrogenic and/or antiestrogenic-related effects [67]

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We chose it in order to optimize the animal experiments to resemble human scenarios, such as an acetaminophen overdose

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