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Figure 2 3.2 Geographical variations The prevalence and incidence of PD vary across countries and regions, influenced by demographic structure, industrialization, access to healthcare, and awareness levels

In PD models, downregulated Bcl-xL expression impairs the resistance of dopaminergic neurons to mitochondrial damage, whereas exogenous upregulation of Bcl-xL markedly alleviates neuronal apoptosis [38, 39]