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Important distinction: "Legal to compound" under 503A is NOT the same as "FDA approved." An FDA-approved drug has gone through full clinical trials and received a New Drug Application (NDA) approval

-tocotrienol binds to the estrogen receptor and activates PI3K/Akt signaling pathways including phosphorylation of protein kinase B (PKB, Akt) and extracellular signal-regulated kinase (ERK) 1/2 [128,168]

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I did my homework, got my baseline bloodwork done, and decided to give it a shot alongside a reduced Nolvadex protocol

Hum Exp Toxicol 41:09603271221127430 Xu Y, Wang H, Zhou S, Yu M, Wang X, Fu K, Qian Z, Zhang H, Qiu L, Liu X, Wang P (2013) Risk of second malignant neoplasms after cyclophosphamide-based chemotherapy with or without radiotherapy for non-Hodgkin lymphoma