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Accumulating evidence demonstrates that roxadustat upregulates HIF expression in ischemia-, hypoxia- or toxication-induced AKI models and can activate multiple target genes to play a renal protective role

These alterations may be explained by the decreasing environmental temperature over the course of the study period

GR activity (U/L) = (dOD s / t) x (440 / (OD-CAL - OD-buffer)) x n, where OD-CAL and OD-buffer are the OD 412nm values of the Calibrator and Assay Buffer, t is the reaction time (20 min recommended) and n is the dilution factor

Shah FT, Sayani F, Trompeter S, Drasar E, Piga A (2019) Challenges of blood transfusions in -thalassemia

Deletion of SRF has been discovered to contribute to several processes involving in epileptogenesis, such as neuroinflammation, mossy fiber sprouting, and cell death [113, 114]