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Description

When neurological symptoms like numbness or tingling are already present, that speed matters

Metanx increases production of tetrahydrobiopterin, a cofactor of endothelial nitric oxide synthase (eNOS), which, theoretically, should counteract eNOS uncoupling, generation of superoxide, superoxide-induced upregulation of inducible nitric oxide synthase (iNOS), and peroxynitrite formation

Nat Rev Dis Primers (2017): Vitamin B12 is essential for normal nervous system function via its role in myelin synthesis and for circulatory system function through its role in red blood cell maturation in the bone marrow