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Jack CR Jr, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, et al

The breakdown of the gut barrier is intimately connected to the hyperactivation of mast cells, a key feature of mast cell activation syndrome (MCAS)

The authors demonstrated that lipid clearance could be systematically tuned through chemical modification of the ionizable lipid structure and that clearance behavior correlated with simple computational measures of lipophilicity

One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages