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Telomere shortening is associated with aging and cellular senescence

Circadian rhythm optimization plays a significant role in healthy aging, as disrupted sleep patterns and irregular hormone cycles have been associated with accelerated aging processes

Empty stomach administration optimizes absorption similar to other peptides, with practical timing of 30 minutes before breakfast for morning administration or 2-3 hours after last meal for evening administration

In this study a series of bivalent phenethylamines with the two phenylalkylamine moieties separated by an aliphatic spacer of increasing length were investigated, with one compound with an 8-carbon linker displaying an 82-fold gain in affinity