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HepG2 cells have significantly higher levels of expression for the transcription factors C/EBP homologous protein (CHOP), activated transcription factor 4 (ATF4), and glucose regulatory protein 78 (Bip) (68)

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doi: 10.1590/1678-4324-ssbfar-2023230300 85 WangT.DongD.ChenT.ZhuJ.WangS.WenW.et al

As our skin ages, we lose the essential connective proteins collagen and elastin

Three matrices were tested: broth culture (BC), cell-free supernatant (CFS), and CP