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Fang H, Judd RL

An overabundance of Cu + /Cu 2+ and Fe 2+ /Fe 3+ can adversely affect cellular function by catalyzing the production of reactive hydroxyl radicals through the Fenton reaction, causing severe oxidative damage and RCD [37]

On top of that, its the most frequently occurring condition among a group of disorders called hamartoma neoplastic syndromes

If blood loss continues long enough that body iron stores are depleted and absorption of dietary iron is inadequate to meet the demand created by increased red blood cell production, then iron becomes a limiting factor and effective erythropoiesis is decreased

doi: 10.1080/09687637.2020.1865273 27 MachoJMudrakJSlepickaP