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Sci Hortic 168:132137

Itaconate and -KG, two key TCA cycle intermediates with immunomodulatory properties, may contribute to SLE pathogenesis by metabolically reprogramming CD4+T cells, thereby influencing the critical balance between pro-inflammatory TH17 and regulatory Treg cell differentiation (111)

Results: The total sample of this study consists of 402 patients, mean age was 59.8 years, 49% female

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