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Gao Y, Chen L, Du Z, Gao W, Wu Z, Liu X, et al

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The SHH-activated group can further be divided into four subgroups, and the non-WNT/non-SHH group can be divided into eight subgroups by DNA methylation or transcriptome profiling [1]

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As discussed in the following sections, this includes the potential to reduce the production of A and the ability to counteract the effects of A oligomers (Aos), a highly pathogenic form of A [31]

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