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SubP and NKA, but not NKB, are localized to sensory nerves that are situated beneath and within the airway epithelium (C-fibers), around blood vessels, and to a lesser degree within airway smooth muscle [37, 71]

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Alpha class of GSTs, which is expressed in most tissues, including brain 45 , is specific for its substrate promiscuity as a consequence of protein flexibility and dynamics in the enzymes active site 46