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Activation of PPAR by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization

Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors

Choi ML, Chappard A, Singh BP, Maclachlan C, Rodrigues M, Fedotova EI, Berezhnov AV, De S, Peddie CJ, Athauda D, Virdi GS, Zhang W, Evans JR, Wernick AI, Zanjani ZS, Angelova PR, Esteras N, Vinokurov AY, Morris K, Jeacock K, Tosatto L, Little D, Gissen P, Clarke DJ, Kunath T, Collinson L, Klenerman D, Abramov AY, Horrocks MH, Gandhi S (2022) Pathological structural conversion of alpha-synuclein at the mitochondria induces neuronal toxicity

Better blood flow and pumps: This supplement's performance benefits not only stem from its ability to increase fat burning and decrease glycogen use, but also from the way it can enhance blood flow to the muscles.[7] Increased blood flow means more nutrients and hormones go where they're needed most during exercise

However, more research is needed to establish the specific actions in the different physiopathological settings [7,8]