glutathione stransferase mu 1 Human S Transferase (GSTm1) Protein Sample size available. Glutathione-S-Transferases as Potential Targets for

Disclosure of interest: none Poster Session II - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.02 - SECONDARY PREVENTION P1002 - ESOC25-228 PREDIABETES AND DIABETES MELLITUS TYPE 2 ONE YEAR AFTER ACUTE ISCHEMIC STROKE Kurt Mlgg 1,2 , Anel Karisik 1,2 , Lukas Scherer 1,2 , Lucie Buergi 1,2 , Benjamin Dejakum 1 , Silvia Komarek 1 , Julian Granna 2 , Christian Boehme 1 , Raimund Pechlaner 1 , Thomas Tll 1 , Michael Knoflach, Stefan Kiechl 1,2 , Susanne Kaser 3 , Alexander Egger 4 , Andrea Griesmacher 4 , Lukas Mayer-Suess 1 1 Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria, 2 VASCage, Centre on Clinical Stroke Research, Innsbruck, Austria, 3 Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria, 4 Central Institute of Clinical Chemistry and Laboratory Medicine, Medical University of Innsbruck, Innsbruck, Austria Background and Aims: The evolution of glycemic status in post-stroke patients remains poorly understood, particularly regarding treatments for type II diabetes mellitus (DM II), such as glucagon-like peptide-1 receptor agonists (GLP-1-RA) and sodium-glucose co-transporter 2 (SGLT-2) inhibitors, which have not been studied in an exclusive post-stroke population

A well-characterized example of this mechanism is the Keap1Nrf2 signaling axis, illustrated in Fig

p-RIPK3

A positive association was observed between copper level in the serum or brain and oxidative stress (Maes et al., 1997

Yan J, Noltner K, Feng J, Li W, Schroer R, Skinner C, et al