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This pattern indicates that tobacco smoke exposure drives T cell differentiation towards the T17 phenotype rather than towards the functionally exhausted or terminally differentiated phenotypes

The continued decline in smoking is a monumental public health achievement that has saved millions of lives and billions in healthcare costs, said Yolonda Richardson, president and chief executive of the Campaign for Tobacco-Free Kids, a Washington, D.C.-based advocacy and research organization

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However, the limited scope of this benefit suggests that the cognitive self-medication hypothesis requires further testing or reconsidering