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The study found that while both methods were safe, topical administration was more effective at reducing inflammation (inhibition of inflammatory factors such as IL-6, TNF-, and Interferon-gamma) and improving tear stability ( Aside from the orally administered probiotic preparations, there is a novel medical therapy called intestinal flora transplantation (FMT) that aims to reinstate the equilibrium of intestinal flora in patients through the transfer of fecal flora from healthy individuals to the patients intestines