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Therefore, it is probable that TG2-mediated modification of GSTP1 affects the interactome of cellular GSTP1, resulting in an alteration of interactions with its binding partners

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To obtain a comprehensive assessment of TGFs metabolic effects, we employed non-targeted metabolomics profiling

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This further regulates vascular tone and the inflammatory microenvironment, indirectly interfering with OSA-related multisystem damage ( The COX pathway plays a key role in the association between OSA and lung cancer: TXA 2 derived from COX-1 is significantly elevated in OSA patients, and non-selective COX inhibitors can reduce the risk of cardiovascular complications by inhibiting COX-1 ( 2 pathway is a key molecular pathway mediating OSA-associated lung cancer progression, and COX-2-specific inhibitors can effectively block this process