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The frequency of injections can vary based on individual needs and healthcare provider recommendations, but they are often administered once or twice weekly

Pflgers Arch European Journal of Physiology 475(5):621635 Qi Y, Wang S, Luo Y, Huang W, Chen L, Zhang Y et al (2020) Exercise-induced nitric oxide contributes to spatial memory and hippocampal capillaries in rats

In a study performed in Korea to distinguish clinical features of early and late-onset LS, it was found that developmental delay was significantly higher in the early onset (before 2 years old) compared to the late-onset (after 2 years old) groups

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Expected diplotype functions, shown in Fig