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Herein, we reviewed a series of natural products targeting mitochondrial oxidative stress, mitochondrial biogenesis, mitophagy, and mitochondrial dynamics

Researchers have found that children with ASD may show metabolic patterns associated with B12 deficiency

In contrast, FOXO4-DRI leverages the elevated expression of FOXO4 and P53 in senescent cells by specifically blocking the interaction between FOXO4 and P53 to promote apoptosis via the P53 signaling pathway (Tao et al., 2016

This method enables the drug to cross the BBB and reach the brain parenchyma, where it can take effect[145,146,147,148,149]

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