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10.1523/JNEUROSCI.3888-10.2010 464 PaceyL

Journal of molecular endocrinology

All-trans retinoic acid (ATRA), a stereoisomeric form of retinoic acid, has been shown to inhibit POMC transactivation and ACTH secretion in murine corticotroph tumor AtT20 cells via inhibition of AP-1 and Nur transcriptional activities (32)

GSH regeneration also counteracts the depletion induced by cancer chemotherapeutic agents, potentially leading to development of cancer drug resistance (171)