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& Farrell, P

Smallmolecule ferroptosis inhibitors and natural compounds show efficacy but are constrained by poor pharmacokinetics and bioavailability

Beyond monotherapies, the strategic modulation of autophagy and ferroptosis offers a powerful approach to augment the efficacy of established cancer treatments and overcome resistance to them

On the other hand, APAP-exposure increases neither caspase-3 nor cleaved-caspase-3 expression which was consistent with previous research that caspase-3 might not play an effect in the APAP-induced liver injury 30 (Figure 5A and 5B)

The treatment of hLf led to the recovery of motor functions and exploratory behaviors in mice