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Description

The dynamic changes in the carnitine pool under physiological and pathological conditions are extremely complex, and existing research may not yet have fully revealed the complete picture

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Whilst the exact pathophysiology of PD still remains unclear, it is believed microvascular trauma, initiated by penile damage during sexual activity or due to repetitive minor trauma, leading to increased proliferation of fibroblasts and recruitment of profibrotic mediators leads to an excessive deposition of collagen