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Use of empirical mode decomposition in ERP analysis to classify familial risk and diagnostic outcomes for autism spectrum disorder

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In the interim analysis it was observed that in individuals who were anti-CCP positive but without inflammatory arthritis at baseline, one year of HCQ was not superior to placebo in preventing or delaying the development of inflammatory arthritis, and the classification of individuals as having RA at 3 years (probabilities of RA development were 34% in the HCQ arm and 36% in the placebo

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