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Clin Cancer Res 29(14):2737, 2023

Another species used for the study of brain metastasis is Drosophila melanogaster

This process was primarily driven by the abnormal proliferation of Fusobacteriota and Bacteroidota: Bacteroidota could efficiently degrade host mucins and polysaccharides, providing essential carbon and energy sources for the community, while Fusobacteriota might exploit their secreted virulence factors, such as leukotoxins and extracellular proteases, to disrupt the mucosal structure 117

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3B), elevating antioxidant enzyme levels like catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) (Lin et al., 2019) (Fig