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10.1002/adma.202414555 53 HaoL.MaoH

doi: 10.7314/APJCP.2013.14.11.6245 186 KuivanenTJeskanenLKyllnenLIsakaKSaarialho-KereU

Under hypercatabolic conditions, its levels are considerably depleted a condition that correlates with pathological severity and has been suggested as an independent predictor of mortality in intensive care unit patients

Consistently, loss of WT1 activity in Wilms' tumour and related malignancies may result in transcriptional derepression of the IGF-1R gene (Gerald et al, 1995)