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Tripathi et al., 2007)

While it may seem paradoxical to both synthesize and destroy a siderophore, an intracellular copper requirement for CueO secretion may ensure that it's siderophore destructive activity is only relevant in the presence of high copper levels

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This will provide protection for the suppository and limit any oil staining that might occur from the materials contained in the suppository base

Andrea Baccarelli of Harvard, seemed to clearly explain his scientific reasoning