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The parametric T-test or non-parametric Kruskal-Wallis test was applied for quantitative variables, after checking the normality, using ShapiroWilk or DAgostinoPearson test, and homoscedasticity, using BrownForsythe and Bartletts test

Changes in the epigenetic landscape of monocytes leading to BDG-induced trained immunity are mediated by the activation of mechanistic target of rapamycin (mTOR) and hypoxia-inducible factor 1 (HIF-1)

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Research has shown that inhibiting PARP-1 can help reduce liver cell injury, decrease inflammation and fibrosis, and enhance antitumor immunity, highlighting its potential as a therapeutic target