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In addition, there is evidence in the literature, including meta-analyses, comparing the effectiveness of combinations of physical and dietary interventions

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10.1016/j.cell.2012.02.035 146 OkaS.TsuzukiT.HidakaM.OhnoM.NakatsuY.SekiguchiM

Some individuals may experience mild adverse effects such as nausea, diarrhea, stomach cramps, or muscle weakness