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By modulating key signaling pathways like STAT3, targeting novel proteins such as RAC2, and interfering with cancer cell metabolism, silibinin demonstrates its potential as a multifaceted therapeutic agent

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Coordination Numbers 10-16 Coordination numbers higher than nine are extremely rare for compounds that bind in \(\kappa\) fashion (form conventional metal-ligand bonds) 14 and usually involve some combination of large metals, sterically undemanding ligands, and special ligand structures that promote higher coordination

10.1242/jeb.082909 44 DicksonA

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