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The endocannabinoid system plays a crucial regulatory role during neurodevelopment [23,24,25,26,27], and disruptions to this system via exposure to extrinsic cannabinoids have well-established neuropathological consequences [28]

Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans

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doi: 10.3389/fnut.2025.1656048 Received 29 June 2025 Accepted 29 August 2025 Published 09 October 2025 Volume 12 - 2025 Edited by Theodoros Androutsakos, National and Kapodistrian University of Athens, Greece Reviewed by Pooja Yadav, Shree Guru Gobind Singh Tricentenary University, India Yansong Fu, Central South University, China Updates Copyright 2025 Ye, Yuan and Cai

This connection is particularly relevant for long COVID sufferers, as the condition is often characterized by ongoing immune system challenges and chronic inflammation