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A recent study reported that oral large dose deucravacitinib (30 mg/kg QD) showed the similar equivalent efficacy to ustekinumab rather than medium dose deucravacitinib (10 mg/kg QD) in IL-23-driven psoriasis-like model ( K17 activates the transcription factor STAT3 under induction of deleterious ROS production in keratinocytes along with Cyclin D1, leading to the hyperproliferation of keratinocytes ( TNF-, IL-6, IL-17 and IL-22 ( Our study also has some limitations

Jiang, P., Gan, M., Yen, S.-H., McLean, P

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In this scenario, simply adding an amino acid or vitamin does not promote wound healing

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