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Description

The free fatty acids and monoacylglycerides that enter the epithelial cells are reincorporated into triglycerides

In doxorubicin-resistant liver cancer (BEL-7402/ADM) cells, apigenin restores drug sensitivity by reducing nuclear factor erythroid 2-related factor 2 (NRF2) expression at both RNA and protein levels through PI3K/AKT pathway inhibition, thereby increasing intracellular doxorubicin [58, 59]