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Furthermore, excessive accumulation of NADH in conjunction with reduced NAD + availability can inhibit glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity in the glycolytic pathway, leading to glucose shunting to the glycolytic branch pathway (Yan et al., 2016

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At median follow-up of 16.9 months, patients in the daratumumab-Pd arm achieved a median PFS of 12.4 months vs

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