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INTRODUCTION Primary sclerosing cholangitis (PSC) is a rare cholestatic disorder of the liver associated with inflammation and injury with fibrosis in the intrahepatic and extrahepatic bile ducts

In the course of this astrogliosis in glaucoma, there is also increased expression of the phagocytosis-related Mac-2 gene and ET-1 by astrocytes, demonstrating both their role in phagocytosis of damaged or dead RGC debris and their involvement in glaucoma-associated vascular dysregulation (Nickells et al., 2012

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In addition, ketogenic diet-induced fibroblast growth factor 21 administration significantly reduced sweet taste and alcohol preference in mice and sweet taste preference in cynomolgus monkeys, and was associated with reduced DA concentrations in the NAc (104)

Handelman, G