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Petersburg Institute of Bioregulation and Gerontology in the late 1980s and 1990s as a synthetic analogue of the natural pineal-gland-extract complex epithalamin

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Amino Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Molecular Formula: C78H123N23O23S2 Molecular Weight: 1815.1 g/mol CAS #: 221231-10-3 InChI: 1S/C78H123N23O23S2/c1-9-41 Proper storage ensures AOD 9604 peptide stability for research applications: Lyophilized Form: Reconstituted Form: Handle peptides in clean laboratory environments using sterile techniques

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Mechanistically, the CD73/A2AR signaling cascade coordinates the de novo synthesis and consumption of GSH with GSSG accumulation and concomitant mitochondrial lipid peroxidation, which links potentially to PKA/E2F1dependent fine-tuning of the ratio of GSR to GPX4

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