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Among children and adolescents with HT, euthyroidism was detected in 52.1% of patients, overt or subclinical hypothyroidism in 41.4%, overt or subclinical hyperthyroidism in 6.5% (7)

927 These results suggest that HDAC3 maintains iron homeostasis through the Hippo/YAP pathway and might represent a target to reduce ferroptosis in iron overload-related diseases

The GST tag can easily be removed following purification by addition of a protease if a suitable protease-cleavage site has been inserted between the GST-tag and the protein of interest (which is usually included in many commercially available sources of GST-tagged plasmids)