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Description

This risk posits a critical limitation on the therapeutic window for senolytic drugs like FOXO4-DRI, demanding a fine balance between efficacy and safety

Antioxidants 12 , 149 (2023)

The balance of the different CRP isoforms, monomeric (mCRP) or native pentameric (nCRP) within the plaque determines the preponderance of a proinflammatory or anti-inflammatory effect, respectively (165)

And they paid their way out of it

Using IsoNet, we construct the isotopologue similarity networks for labeled metabolites in live cells and mice, and discover hundreds of putative unknown metabolic reactions