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Furthermore, owing to the potential of multi-organ involvement, multidisciplinary care is often required [109,110,111,112]

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Collectively, GGCT emerges as a pivotal metabolic orchestrator in HCC and PCa, functioning as a bidirectional switch that diverts Gln toward GSH biosynthesis for redox defense while enhancing Glc-fueled TCA anaplerosis to sustain cell proliferation