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Description

P1284 Gryglewska B

Significance of glutathione in lung disease and implications for therapy

Tissue-Specific Distribution : The enhanced bioavailability allows for preferential accumulation in glutathione-dependent organs, particularly the liver for detoxification processes and the lungs for respiratory support against oxidative stress

This syndrome is characterized by clinical symptoms of sickness behavior such as leaden paralysis of the limbs, hypersomnia, and hyperphagia/weight gain, while mood reactivity is unimpaired, i.e., mood brightens in response to positive events (according to DSM-5 criteria for MDD with atypical features), while still suffering from lack of concentration and higher levels of exhaustibility as in melancholic MDD [99]