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In this matter, neuronal death is thought to be a consequence of the inhibition of mitochondrial complex I, which leads to a reduction in the energy supply and subsequent collapse of the mitochondrial membrane potential [66]

Storage conditions Store at room temperature, in a cool, dry place protected from light

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Labwork at that time was notable for an elevated uric acid of 10.6mg/dl (reference range: 3.5 - 8.5 mg/dl.) Out of concern for TLS precipitating hyperuricemia in the setting of a high-grade tumor in addition to starting a new chemotherapy regimen, the patient was additionally given 10mg of rasburicase and started on 300mg of allopurinol daily