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In Chronic Diseases: Half of the above dosage is required repeatedly at intervals of 1 to 2 weeks In healthy animals: Half of the above dosage

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The study also revealed that AS-IV could alleviate iron-dependent cell death in cardiomyocytes by activating the Nrf2 signaling pathway and enhancing the expression of GPx4, thereby attenuating oxidative stress induced by DOX (Luo et al., 2021a)

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Long-term studies in animals to evaluate carcinogenic potential have not been done