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The metabolic plasticity of cancer is not restricted only to cancer cells but extends throughout the TME (184, 185), as seen in CAFs that secrete lactate, lung mesenchymal-derived cells that transfer lipids, suppressing the functioning of NK cells, and arginine-depleting collagen-producing TAMs, leading to the suppression of CD8 + T cell functions

pylori) antigens may be involved in the development of AITD, and one study reported that up to 85% of patients with autoimmune atrophic thyroiditis have H