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ChemMedChem 14:927937

22 On the other hand, certain biomolecules, such as nesfatin-1, can reduce ASIC1a protein levels through the MAPK/ERK and NF-B pathways, thereby inhibiting acidosis-induced oxidative stress, inflammation and apoptosis in chondrocytes, which has a beneficial effect on alleviating arthritis symptoms

10.1016/j.cellimm.2021.104364

About 35 mg to about 135 mg of mannitol

To improve purification of rMCP, insoluble pellet fractions were resuspended in incubation buffer (20 mM Tris-HCl, pH 7.4, 0.5 M NaCl, 6 M GdmCl) on ice for 20 min