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Although these findings do not prove that gluten alone drives thyroid disease, they support the concept that a dysbiotic, permeable gut may lower the threshold for thyroid-directed autoimmunity in susceptible hosts ( 3 Immune cross-reactivity between gluten, HT, and CD 3.1 Molecular mimicry as a general autoimmune mechanism Molecular mimicry describes the situation in which foreign antigens and host antigens share sufficient structural similarity to permit cross-recognition by adaptive immune cells or antibodies

PMID: 23370317

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PMID 18931697